Current Projects

  • The induction of hypothermia during resuscitation by emergency physicians in cooperation with Berlin fire department
  • Development of new biomarkers after resuscitation to optimize the therapy and early assessment of the prognosis and to characterize the severity of the hypoxic brain injury
  • Characterization of the inflammatory syndrome after resuscitation by biomarkers
  • Evaluation of the significance of the ”gray-white matter ratio“ in cCT during the early phase after resuscitation for the assessment of the neurological prognosis
  • Infrared pupillometry after resuscitation for guidance of the therapy and early assessment of the prognosis (NPi: Neuro-Pupillo-Index)
  • Study of the cognitive performance after cardiac arrest by means of a standardized questionnaire during the follow-up period
  • Kidney function after cardiac arrest; measurement of Neutrophil gelatinase-associated lipocalin (NGAL) in the urine during the post-arrest period
  • Study of the liver function (CYP-450 system) after resuscitation taking hypothermia into consideration by means of LiMAx (LiMAx-HYPO trial). The LiMAx test is based on the hepatocyte-specific metabolism of the 13C-labelled substrate by the cytochrome P450 1A2 enzyme.
  • Evaluation of new biomarkers for early assessment of prognosis; serial examination of plasma choline after resuscitation
  • Study of Plavix® metabolism after cardiac arrest during hypothermia treatment
  • Near infrared spectroscopy of the cerebral oxygen saturation (NIRS) after cardiac arrest and hypothermia at the intensive care unit (NIRS-ICU trial)
  • Study of the value of monitoring by NIRS during the therapy of malignant cardiac arrhythmias
  • Evaluation of inhalative sedation after cardiac arrest